Hormone therapy: restoring balance and revitalizing vitality

Hormone therapy is a modern medical intervention that precisely regulates the human endocrine system. It aims to supplement key hormones that gradually decrease with age, restoring the body's physiological balance. Through individualized assessments and treatment plans, it effectively improves various symptoms caused by hormonal imbalances, including fatigue, mood swings, cognitive decline, and sexual dysfunction. Especially in perimenopausal women and middle-aged men, scientifically and reasonably administered hormone supplementation can significantly enhance quality of life, delay the aging process, and restore vitality. As an important pillar of anti-aging medicine, modern hormone therapy - especially bioidentical hormone replacement therapy (BHRT) - is becoming the preferred strategy for health management due to its excellent safety and effectiveness.

Hormones: Messengers and Regulators of Life

Hormones, also known as hormone, are high-potency bioactive substances secreted by endocrine glands or endocrine cells. They act as precise messengers within the body, traveling through the bloodstream to various parts of the body, where they act on specific target cells or target organs to regulate their physiological and biochemical activities. The physiological functions of hormones are extensive and crucial, encompassing multiple aspects such as growth and development, metabolism, reproduction, stress response, and emotional regulation. They maintain the stability of the body's internal environment and ensure the coordinated progression of various physiological activities.

• Female hormones: The core of life nurturing and health maintenance

  
  For women, estrogen and progesterone are the most central hormones, collectively known as female hormones, primarily secreted by the ovaries. These hormones are responsible for women's reproductive health, secondary sexual characteristics, bone health, cardiovascular protection, mood, and cognition. Throughout a woman's life, she goes through different physiological stages such as puberty, childbearing age, perimenopause, and postmenopausal period, during which her hormone levels undergo regular changes, profoundly affecting her physiological and psychological states.

  
  

• Testosterone: The Key to Vitality, Strength, and Reproduction

  
  For males, testosterone is the primary male hormone, primarily secreted by the testes. Additionally, growth hormone and insulin-like growth factor are also crucial for male health. They are responsible for male reproductive function, muscle and bone growth, physical and mental energy, metabolism and cardiovascular health, cognition and mood, among others.

During the middle-aged stage (usually referring to the age range of 35-60), both men and women experience significant changes in hormone levels. Women enter perimenopause, during which estrogen and progesterone levels decline sharply; men, on the other hand, face a gradual decline in testosterone and growth hormone levels. These changes not only affect reproductive ability but are also closely linked to overall health status, quality of life, and the aging process.

* References
Andersen, M. L., Hachul, H., Ishikura, I. A., & Tufik, S. (2023). Sleep in women: a narrative review of hormonal influences, sex differences and health implications. Frontiers in Sleep, 2, 1271827.
Rojas-Zambrano, J. G., Rojas-Zambrano, A. R., Rojas-Zambrano, A. F., Barahona-Cueva, G. E., Rojas-Zambrano, A., & Rojas-Zambrano Sr, A. F. (2025). Benefits of Testosterone Hormone in the Human Body: A Systematic Review. Cureus, 17 (2).

Hormonal imbalance and sub-optimal health: The hidden challenge of mid-life health

The balance of hormones is the foundation for maintaining normal physiological functions and physical and mental health. When individuals enter the middle-aged stage between the ages of 35 and 60, the natural decline in hormone secretion or imbalances caused by other factors often become the root cause of many sub-health symptoms. Sub-health states, described as a "grey zone" between health and disease, are characterized by reduced vitality, decreased function, and adaptability, but they have not yet reached clear diagnostic criteria for diseases. These sub-health states manifest in various aspects of the body:

• Energy systemPersistent fatigue, lack of energy, and decreased vitality.

• Emotions and sleep: Emotional fluctuations, irritability, anxiety, depressive tendencies, insomnia, or poor sleep quality.

• Metabolism and body weightUnexplained weight gain or difficulty in losing weight, slowed metabolism, abdominal fat accumulation, etc.

• Skin and hairDry skin, loss of elasticity, sparse hair, hair loss, and stubborn acne.

• digestive systemIndigestion, constipation or diarrhea, irritable bowel syndrome, etc. are also related to hormone levels.

• Sexual function and reproductive system: Decreased sexual desire, irregular menstruation or dysmenorrhea in women, erectile dysfunction in men, etc.

• Other SymptomsSuch as hot flushes, night sweats, joint pain, memory decline, difficulty concentrating, dizziness, palpitations, etc.

These sub-health symptoms often do not appear singly, but rather, multiple symptoms are intertwined, seriously affecting individuals' quality of life and work efficiency. Surveys show that the incidence rate of sub-health among the population is between 45% and 70%, with the high-incidence age group concentrated in the 35-60 age range, especially among middle-aged intellectuals, white-collar workers, entrepreneurs, and other mental laborers. Research from the American Academy of Anti-Aging Medicine points out that hormone secretion decreases at a rate of 15% per decade, and this physiological decline is an important internal cause of sub-health in middle age.

Image: Schematic diagram of the trend of hormone levels changing with age (data for reference only, illustrating trends)

* References
Cybulska, A. M., Szkup, M., Schneider-Matyka, D., Skonieczna-Żydecka, K., Kaczmarczyk, M., Jurczak, A., ... & Grochans, E. (2020). Depressive symptoms among middle-aged women—understanding the cause. Brain sciences, 11 (1), 26.

BHRT: Exploring a More "Natural" Approach to Hormonal Balance

Bioidentical hormones are hormones that are chemically identical to those produced by the body. They are biological preparations that are cultivated in professional biological laboratories and share the same biological properties as hormones naturally produced by the human body, hence the name "bioidentical". Therefore, after such biological preparations enter the human body, various receptors and endocrine glands will not distinguish between the hormones they produce and those produced naturally by the body, and the immune system will not recognize them as "antigens (foreign substances)" and trigger an immune response that reduces the effectiveness of the biological preparations.

Bioidentical Hormone Replacement Therapy (BHRT) involves analyzing blood, urine, saliva, and other bodily fluids, and integrating personal medical history, family history, physical examination results, and functional medicine test results to understand the levels of various hormones in the body, thereby determining the type and dosage of bioidentical hormones that need to be supplemented. Based on the different hormonal states within each patient's body, personalized bioidentical hormone ratios are formulated to achieve the supplementation of hormones required for the normal functioning of various bodily functions, such as bioidentical estrogen, progesterone, testosterone, dehydroepiandrosterone, melatonin, pregnenolone, growth hormone, etc. Treatment is administered through direct injection or subcutaneous infusion.

Bioidentical hormone therapy is a treatment method aimed at optimizing human hormone levels, primarily for individuals aged 35 and above, especially postmenopausal women, to maximize patients' quality of life and various bodily functions. Bioidentical hormones are biologically identical to hormones produced in the body and are the most effective therapy for replacing missing human hormones (officially certified by authoritative institutions such as the US FDA).

• authority: Officially certified by the US FDA

• maturitySince the 1980s, European and American countries have completed over 30 years of clinical trials on drinking

• accuracyBased on the customer's functional medical testing indicators, personalized customization of homologous hormone compound biological preparations

• persistenceSubcutaneous injection and sustained release technology achieves long-lasting and stable release, simulating physiological secretion status, and yields better therapeutic effects compared to injection therapy

• "Bioidentical Hormones" Core AdvantagesThe molecular structure is consistent with the biological properties and structure of hormones naturally secreted by the human body

Bioidentical Hormone Replacement Therapy (BHRT) is currently the only program in the field of anti-aging medicine that has been widely and long-term clinically applied worldwide and is certified by the US FDA.

Project plan objectives

• Achieve integrated anti-aging: "organ health" and "restoration of youthful state"; protect brain function, control body composition, enhance metabolism and immunity, protect female glands, and protect intimate and urinary systems.

• The main symptoms alleviated include: emotional instability, irritability and chest tightness, weight gain due to fat accumulation, insomnia and headache, memory decline, forgetfulness, hot flushes, night sweats, fatigue and weakness, decreased sexual function in men, menstrual irregularities and vaginal dryness in women, skin sagging and aging, increased wrinkles, osteoporosis, and cardiovascular and cerebrovascular diseases.

* References
Lind, T., Cameron, E. C., Hunter, W. M., Leon, C., Moran, P. F., Oxley, A., & Gerrard, J. (1979). A prospective, controlled trial of hormone replacement therapy given to postmenopausal women. BJOG: An International Journal of Obstetrics & Gynaecology, 86, 1-30.
Hertoghe, T., Bassin, L., Hunter, A., Williams, G., Davies, S. R., & Kruger, J. (2004). Bio-identical Hormone Replacement Therapy. Journal of Complementary Medicine: CM, The, 3 (5).
Dilks, A., & Soos, E. (2019). Bioidentical hormone replacement therapy: implications for practice. Journal of Aesthetic Nursing, 8 (4), 166-171.

It's not just about "living a long life", but more about "living a quality life"

Be.U Med firmly believes that the ultimate value of genuine health investment goes far beyond merely extending the years of life. It lies more in ensuring that at every stage of life, whether it's the peak of one's career or the leisurely second half of life, one can maintain abundant energy to pursue dreams, possess a clear and sharp mind to tackle challenges, enjoy balanced and stable emotions to appreciate the beauty of life, and have a robust physique to explore the vastness of the world.

• World-class medical and testing technology & internationally certified laboratories and medical institutions

• Experienced international team of functional medicine experts & in-depth personalized consultation and treatment plan

• Health management closed-loop services featuring technological foresight, interdisciplinary collaboration, and team integration

**Disclaimer: This content is for reference and academic exchange only. All content is quoted from relevant academic research and does not represent the views and judgments of Be.U Medical Group. It cannot replace professional medical advice, diagnosis, or treatment. If you have any health concerns, please consult a licensed professional doctor.